Acinetobacter is a diverse genus consisting of more than 50 species, the majority of which are harmless environmental bacteria. However, a handful of Acinetobacter spp., belonging to the Acinetobacter calcoaceticus-A. baumannii (ACB) complex, pose a significant public health burden due to their association with hospital-acquired infections (HAI). Among ACB complex pathogens, A. baumannii is frequently encountered in intensive care units (ICUs) of hospitals where it usually infects debilitated patients with impaired host defences and disrupted normal flora. A. baumannii most commonly manifests in hospital-acquired pneumonia and bloodstream infections while also contributing to urinary tract infections, meningitis and wound infections.

A.baumannii has built a formidable global reputation due its robust antimicrobial resistance (AMR) capabilities against a wide range of antibiotics including carbapenems, making it a priority organism for the World Health Organization (WHO).

Project title: Genomic landscape of prominent XDR Acinetobacter clonal complexes from Dhaka, Bangladesh

Progress: Completed

[Our lab is collaboratively working with NSU genome research institute]

Publication:

Title: Genomic landscape of prominent XDR Acinetobacter clonal complexes from Dhaka, Bangladesh. BMC Genomics, 23(1), 802.

Rahman, A., Styczynski, A., Khaleque, A., Hossain, S. A., Sadique, A., Hossain, A., Jain, M., Tabassum, S. N., Khan, F., Bhuiyan, M. S. S., Alam, J., Khandakar, A., Kamruzzaman, M., Ahsan, C. R., Kashem, S. B. A., Chowdhury, M. E. H., & Hossain, M. (2022). https://doi.org/10.1186/s12864-022-08991-x